蒙特利尔认知评估量表对职业性慢性苯中毒患者认知功能的观察

司徒洁; 林春梅; 朱德香; 李智民

doi:10.16369/j.oher.issn.1007-1326.2018.01.003

蒙特利尔认知评估量表对职业性慢性苯中毒患者认知功能的观察

Observation of cognitive function of occupational chronic benzene poisoning patients with Montreal cognitive assessment

摘要

摘要:
目的利用蒙特利尔认知评估量表研究职业性慢性苯中毒患者认知功能的特点。
方法收集职业性慢性苯中毒患者39例作为观察组, 与观察组性别、年龄、学历相匹配的健康人群39例作为对照组。两组分别使用蒙特利尔认知评估(Montreal cognitive assessment, MoCA)量表来探讨苯中毒患者的认知功能特点。
结果观察组MoCA量表评分平均总得分(24.10 ±3.82)分, 对照组平均总得分(25.36 ±2.34)分; 两组总得分比较, 差异均无统计学意义(P>0.05)。同对照组相比, 观察组视空间与执行能力、命名、注意力与计算力3个因子分值降低, 差异有统计学意义(P < 0.05)。
结论职业性慢性苯中毒可能对患者在视空间与执行能力、命名、注意力与计算力方面有一定影响。

Abstract:
Objective The cognitive function of patients with occupational chronic benzene poisoning was investigated.
Methods The Montreal cognitive assessment (MoCA) was used to survey both 39 patients with occupational chronic benzene poisoning and 39 healthy subjects.
Results The survey showed that difference of MoCA testing scores between these two groups (24.10 ±3.82 vs. 25.36 ±2.34) had no statistical significance(P>0.05). However, there were statistically significant differences of 3 factors including the visuospatial and executive functions, naming functions, and attention between them(P=0.001, 0.029, 0.034, respectively).
Conclusion The patients with occupational chronic benzene poisoning might have damages to central nervous system on aspects related to visuospatial and executive functions, naming functions, and attention.

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