周浩, 陈旭玮, 马锦华, 薛婷, 吴琳, 肖吕武, 刘斌, 刘移民. 广东省低浓度接尘男性健康工人肺通气功能预计值初探[J]. 职业卫生与应急救援, 2015, 33(3): 151-155. DOI: 10.16369/j.oher.issn.1007-1326.2015.03.001
引用本文: 周浩, 陈旭玮, 马锦华, 薛婷, 吴琳, 肖吕武, 刘斌, 刘移民. 广东省低浓度接尘男性健康工人肺通气功能预计值初探[J]. 职业卫生与应急救援, 2015, 33(3): 151-155. DOI: 10.16369/j.oher.issn.1007-1326.2015.03.001
ZHOU Hao, CHEN Xuwei, MA Jinhua, XUE Ting, WU Lin, XIAO Lvwu, LIU Bin, LIU Yimin. Prediction equations of pulmonary function in male healthy workers exposed to low-level dust in Guangdong Province[J]. Occupational Health and Emergency Rescue, 2015, 33(3): 151-155. DOI: 10.16369/j.oher.issn.1007-1326.2015.03.001
Citation: ZHOU Hao, CHEN Xuwei, MA Jinhua, XUE Ting, WU Lin, XIAO Lvwu, LIU Bin, LIU Yimin. Prediction equations of pulmonary function in male healthy workers exposed to low-level dust in Guangdong Province[J]. Occupational Health and Emergency Rescue, 2015, 33(3): 151-155. DOI: 10.16369/j.oher.issn.1007-1326.2015.03.001

广东省低浓度接尘男性健康工人肺通气功能预计值初探

Prediction equations of pulmonary function in male healthy workers exposed to low-level dust in Guangdong Province

  • 摘要: 目的 探讨广东省低浓度接尘男性健康工人肺通气功能各项指标的分布特征,并初步拟合出该人群的肺通气功能正常预计值公式,为其肺通气功能检查结果的评估提供参考。 方法 选取广州地区从事机械加工工作的低浓度接尘男性健康工人2 057名,分析其肺通气功能,并试拟出各项指标的预计值公式,再进一步对结果进行验证。 结果 用力肺活量(FVC)、第一秒用力呼气容积(FEV1)、第一秒用力呼气容积占用力肺活量比值(FEV1/FVC)、最大呼气中期流速(MMEF)四个指标的实测值均随年龄增加而降低(相关系数依次为-0.426、-0.528、-0.377、-0.298,P<0.01);除FEV1/FVC外,另三个指标随着身高增加而增加(相关系数分别为:FVC 0.609、FEV1 0.585、MMEF 0.278,P<0.01);除MMEF外,另三个指标和体重有一定相关性(相关系数分别为:FVC 0.222、FEV1 0.093、FEV1/FVC-0.248,P<0.01)。多元线性回归分析结果提示FVC的影响依次为身高、年龄、体重(β=0.052、-0.018、0.010,P<0.01);FEV1的影响依次为身高、年龄(β=0.048、-0.021,P<0.01);MMEF的影响因素为年龄、身高(β=-0.036、0.035,P<0.01);FEV1/FVC的影响因素为年龄、体重(β=-0.157、-0.137,P<0.01)。新拟合公式计算的预计值与华南地区人群常模公式(1990年)不甚一致,但新预计值与实测值间的差异均无统计学意义(t=1.75、1.67、0.74、0.76,P>0.05)。新拟合公式评价的FVC、FEV1异常率均高于华南地区常模,差异均有统计学意义(χ2=20.83、17.05,P<0.01)。 结论 本地区健康男性工人的各项肺通气功能指标与身高、年龄、体重存在相关性,新拟合预计值公式比地区常模更符合职业接尘工人的实际情况,建议针对职业接尘工人这一特殊群体,使用调整的地区常模预计值公式进行评价。

     

    Abstract: Objective The aim of this study was to explore the distribution of pulmonary function of male healthy workers occupationally exposed to very low level dust in Guangdong Province. Moreover,the prediction equations of standardized pulmonary function were established and the reference value was provided. Methods A total of 2 057 male healthy workers in Guangzhou were studied. The distribution of the pulmonary function and affecting factors were analyzed to determine the prediction equation. Results Forced vital capacity(FVC),forced expiratory volume in one second (FEV1), FEV1/FVC and maximal mid-expiratory flow curve (MMEF) decreased gradually with age (r=-0.426,-0.528,-0.377,-0.298,respectively, P<0.01). FVC, FEV1 and MMEF increased gradually with height(r=0.609, 0.585,0.278,respectively, P<0.01). FVC, FEV1 and FEV1/FVC were associated with weight(r=0.222, 0.093,-0.248,respectively, P<0.01). The results of multiple linear regression analysis showed that FVC was affected by height, age and weight(β=0.052, -0.018, 0.010, respectively, P<0.01),FEV1 was affected by height and age (β=0.048,-0.021,P<0.01), MMEF was affected by age and height (β=-0.036, 0.035,repsectively,P<0.01) and FEV1/FVC was affected by age and height (β=-0.157, -0.137, respectively, P<0.01). The values of the present prediction equations were different from the predicted values of the Southern China area equations announced in 1990. The abnormal rates of FVC and FEV1 by our prediction equations were higher than the Southern China area equations(χ2=20.83,17.05,respectively,P<0.01). Conclusion The pulmonary function of male healthy workers was related to age,height and weight. Moreover,the present prediction equations of pulmonary function for the workers were more suitable and recommended.

     

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