Abstract: Objective To evaluate the effectiveness of Medical Training Therapy(MTT)in the clinic rehabilitation of occupational chronic n-Hexane poisoning patients. Methods A total of 24 cases who suffered from occupational chronic n-Hexane poisoning(OCHP)from January 2012 to December 2013, as observed group, were treated with multiple methods including MTT, low frequency impulse electrotherapy, computerized modulated medium frequency therapy, electro-acupuncture, manual stretching and massage. The automatic VAS of triceps surae pain,the reducing distances of numb feeling of limb skin,the circumference and strength of limbs muscle,the standing balance ability,the motor functions of lower limbs and the ADL(activities of daily living) scores were evaluated before and 6 weeks, 3 months, 6 months and 12 months after treatment. These items were compared with those in other 50 poisoning cases who were treated with same way except for MTT from December 2009 to September 2011. Results 1)Two groups of patients had similar symptoms and signs including triceps surae pain, numb feeling on limb skin,amyotrophy, limited or dysfunctional motor functions of lower limbs and the decline of ADL scores before they were treated. 2) After 6-week's treatment, two groups of patients had no obvious improvement(both P>0.05).3)After 3 and 6 months' treatment, the two groups of patients had obvious improvement(both P<0.05), but the MTT treated group improved much better than the other group(both P<0.05). Conclusion MTT with low frequency impulse electrotherapy, computerized modulated medium frequency therapy, electro-acupuncture, manual stretching and massage were very important and effective in the clinic rehabilitation of OCHP.