钱秀荣, 陈林, 刘啸文, 徐酩, 朱宝立, 张恒东. 某蓄电池厂作业工人血铅、尿铅与指甲铅检测结果分析[J]. 职业卫生与应急救援, 2017, 35(5): 409-411, 415. DOI: 10.16369/j.oher.issn.1007-1326.2017.05.003
引用本文: 钱秀荣, 陈林, 刘啸文, 徐酩, 朱宝立, 张恒东. 某蓄电池厂作业工人血铅、尿铅与指甲铅检测结果分析[J]. 职业卫生与应急救援, 2017, 35(5): 409-411, 415. DOI: 10.16369/j.oher.issn.1007-1326.2017.05.003
QIAN Xiurong, CHEN Lin, LIU Xiaowen, XU Ming, ZHU Baoli, ZHANG Hengdong. Investigation on blood, urine and nail lead levels of workers in a battery plant[J]. Occupational Health and Emergency Rescue, 2017, 35(5): 409-411, 415. DOI: 10.16369/j.oher.issn.1007-1326.2017.05.003
Citation: QIAN Xiurong, CHEN Lin, LIU Xiaowen, XU Ming, ZHU Baoli, ZHANG Hengdong. Investigation on blood, urine and nail lead levels of workers in a battery plant[J]. Occupational Health and Emergency Rescue, 2017, 35(5): 409-411, 415. DOI: 10.16369/j.oher.issn.1007-1326.2017.05.003

某蓄电池厂作业工人血铅、尿铅与指甲铅检测结果分析

Investigation on blood, urine and nail lead levels of workers in a battery plant

  • 摘要:
    目的 通过对某蓄电池厂工作人员血铅、尿铅及指甲铅水平的分析, 探讨三者在职业病诊断中的价值。
    方法 留取该企业203名作业工人静脉血标本、尿标本以及指甲标本, 用石墨炉原子吸收光谱法测定血铅、尿铅以及指甲铅水平, 并对数据进行统计学分析。
    结果 该企业铅烟时间加权平均浓度(CTWA)为(0.31 ±0.37) mg/m3, 铅尘CTWA为(0.28 ±0.50) mg/m3。员工血铅均值为(280.37 ±164.86)μg/L, 异常率为22.7%;尿铅均值为(0.035 ±0.042) mg/L, 异常率为11.3%;指甲铅均值为(1 407.96 ±2 625.26)μg/g。男性工人血铅、尿铅、指甲铅水平均高于女性工人, 差异有统计学意义(P < 0.01或0.05)。不同工龄组工人血铅、尿铅异常率差异均无统计学意义(P>0.05)。血铅、尿铅水平和指甲铅水平均存在相关关系(r=0.544、0.546, P < 0.01)。
    结论 该蓄电池厂铅作业工人血铅、尿铅、指甲铅均有异常, 指甲铅和血铅水平有较好的相关性。指甲铅水平可作为职业性慢性铅中毒诊断的一个辅助指标, 值得进一步探讨。

     

    Abstract:
    Objective To observe the relation among blood, urine and nail lead levels and explore the value of these indexes in the diagnosis of occupational disease.
    Methods Blood samples, urine samples and nail samples of 203 workers were collected in a battery plant. The concentrations of blood lead, urine lead and nail lead were determined with graphite furnace atomic absorption spectrometry.
    Results The average of lead fume and dust concentration were(0.31 ±0.37)mg/m3 and (0.28 ±0.50)mg/m3, respectively. The average of blood lead concentration was(280.37 ±164.86)μg/L with the abnormality 22.7%. The mean value of urine lead concentration was(0.035 ±0.042)mg/L with the abnormality 11.3%. The average of nail lead concentration was(1 407.96 ±2 625.26)μg/g. Blood lead, urine lead and nail lead levels of male workers were higher than those of female workers(P < 0.01 or 0.05). The variation of both blood and urine lead levels among workers with different working time were not statistically significant different(P>0.05). There was a linear relation between blood lead and nail lead(r=0.544, P < 0.01), and between urine lead and nail lead(r=0.546, P < 0.01).
    Conclusion The abnormality of blood lead, urine lead and nail lead levels among these lead-exposed workers in this battery plant is high. The level of nail lead has a good relation with blood lead and could be used as an auxiliary indicator for the diagnosis of occupational chronic lead poisoning.,

     

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