五种环氧树脂固化剂的刺激/腐蚀性试验结果及安全防护

洪丽玲; 房朋; 王婷; 徐桐桐; 杜秀明

doi:10.16369/j.oher.issn.1007-1326.2021.03.020

五种环氧树脂固化剂的刺激/腐蚀性试验结果及安全防护

Analysis of irritation/corrosivity test results of five epoxy resin curing agents and their safety protection

摘要

摘要:
目的定性和半定量评价环氧树脂固化剂对哺乳动物皮肤局部的刺激或腐蚀作用，为皮肤防护提供依据。
方法按照GB/T 21604—2008《化学品急性皮肤刺激性/腐蚀性试验方法》，对5种常见环氧树脂固化剂进行检测。
结果 5种环氧树脂固化剂中，异氰酸酯和酸酐环氧树脂固化剂两种产品皮肤刺激强度为轻刺激性，皮肤刺激反应积分均值分别为1.75和0.75；聚醚胺环氧树脂固化剂的皮肤刺激强度为中刺激性，皮肤刺激反应积分均值为3.25；酚醛类和聚酰胺环氧树脂固化剂两种产品出现皮肤腐蚀性反应。
结论五种环氧树脂固化剂对新西兰家兔皮肤有不同程度的刺激作用，甚至导致皮肤腐蚀，在实际使用过程中应当做好安全防护。

Abstract:
Objective To evaluate qualitatively and semi-quantitatively the irritating/corrosive effect of epoxy resin curing agent on mammalian skin, and provide protective guideline for human dermal exposure.
Methods The acute dermal irritation/corrosivity test of 5 kinds of epoxy curing agents was carried out according to the guideline entitled with Chemicals-test method of acute dermal irritation/corrosion(GB/T 21604-2008).
Results The mean skin reaction scores of isocyanate epoxy resin curing agent and anhydride epoxy resin curing agent were 1.75 and 0.75 respectively, and ranked as the mild irritation intensity. The mean skin reaction score of polyether amine epoxy resin curing agent was 3.25 and ranked as moderate irritation. Both Phenolic resin and polyamide epoxy resin curing agent had skin corrosive reaction.
Conclusions Five epoxy resin curing agents can stimulate the skin of New Zealand rabbits in different degrees, and even lead to skin corrosion, so dermal protection should be done in the actual use process.

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