Objective To investigate whether the POCT technique can replace routine test for detecting myocardial damage markers in patients with acute coronary syndrome (ACS).
Methods A total of 60 patients with ACS were randomly divided into the POCT group and the routine test group, respectively. The POCT or traditional laboratory testing methods was used for detection of myocardial damage markers, such as myoglobin (Myo), cardiac troponin I (cTnI), creatine kinase isoenzyme (CK-MB). The reporting time of testing results, the changing tendency of testing indicators during the emergency visits, on the third day and the seventh day of admission, days of hospitalization and fatality rate within 28 days were recorded and also compared.
Results The reporting time of POCT(61.10 ±27.45) min were statistically shorter than that of routine test(76.50 ±31.25)min during emergency visit. In addition, there were also statistically significant difference (P < 0.05) of the reporting time on third days(140.67 ±81.50)min vs. (220.90 ±63.14)min and on seventh days(151.83 ±65.22)min vs. (198.63 ±60.39)min after admission. The changes of myocardial injury markers in the two groups were basically consistent. There was no significant difference in hospitalization time, hospitalization expenses and fatality rate within 28 days between these two groups (P>0.05).
Conclusion Compared with routine methods, detection of myocardial markers in patients with ACS by POCT can save time for early diagnosis and follow-up treatment of ACS. And POCT is very close in terms of hospitalization expenses. POCT technique may be considered as an alternative to routine test.
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